Association of Hydrogen Ion Ejection with Oxidative Phosphorylation by Mouse Liver Mitochondria
نویسندگان
چکیده
منابع مشابه
Oxidative phosphorylation by mitochondria of transplantable mouse hepatoma and mouse liver.
The synthesis of high energy phosphate bonds as adenosinetriphosphate (ATP) during glycolysis and during certain aerobic oxidations is generally regarded as the probable mechanism mediating much of the energy necessary for cell maintenance and growth. In tumor tissue the phosphorylation mechanism of energy transfer has been identified primarily with the process of glycolysis (6-9) which is well...
متن کاملpH effects on oxidative phosphorylation of rat liver mitochondria.
TOBIN, RICHARD B., CARL R. MACKERER, AND MYRON A. ~EHLMAN. PH ejf’ects on oxidative phosphorylation of rat liver mitochondria. Am. J. Physiol. 223(l) : 83-88. 1972.-Respiration and oxidative phosphorylation of rat liver mitochondria were studied polarographically as functions of the pH of the incubation medium. Oxidation of pyruvate in the presence of ADP (state 3) and succinate, pyruvate, a-ke...
متن کاملStreptolydigin, an inhibitor of oxidative phosphorylation in rat liver mitochondria.
Streptolydigin interferes with oxidative phosphorylation in rat liver mitochondria. The agent acts primarily as an uncoupler of respiration-associated phosphorylation but also impairs respiration to various degrees depending on the substrate. Streptolydigin partially inhibits electron flow at a point past the cytochrome b and prior to the cytochrome c reduction site. Streptolydigin also inhibit...
متن کاملOxidative phosphorylation with endogenous substrates of mitochondria.
During recent studies of oxidative phosphorylation in rat liver mitochondria (2, 3)) we observed that preparations isolated with meticulous care catalyzed a significant uptake of inorganic orthophosphate in the absence of any added substrate. Although incidental observations of endogenous activity of isolated mitochondria have been noted by others (P9), no extensive study of this phenomenon has...
متن کاملUncoupling of oxidative phosphorylation by cadmium ion.
Mitochondria from rat liver were isolated in 0.25 M sucrose according to Schneider (5) and suspended in 1 ml. of 0.25 M sucrose per gm. of fresh liver. Rabbit liver mitochondria, used only for the experiments in Table I, were prepared by grinding the tissue in 0.25 M sucrose in a Waring blendor at reduced speed (6) and were suspended in 1 ml. of sucrose solution per 2 gm. of liver. The reaction...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1966
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(18)96536-1